Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA. Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA. Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA. Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch, National Human Genome Research Institute, Bethesda, MD, USA. Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN, USA.